GSK3β-IN-1a

CAS No. 1139875-74-3

GSK3β-IN-1a( —— )

Catalog No. M10492 CAS No. 1139875-74-3

GSK3β-IN-1a is a relatively selective and potent GSK-3β inhibitor with IC50 of 64 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 188 In Stock
10MG 281 In Stock
25MG 487 In Stock
50MG 677 In Stock
100MG 916 In Stock
200MG 1256 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    GSK3β-IN-1a
  • Note
    Research use only, not for human use.
  • Brief Description
    GSK3β-IN-1a is a relatively selective and potent GSK-3β inhibitor with IC50 of 64 nM.
  • Description
    GSK3β-IN-1a is a relatively selective and potent GSK-3β inhibitor with IC50 of 64 nM; induces replication of growth-arrested R7T1 β cells in a dose-dependent manner with EC50 of 1.1 uM, likely mediates β-cell proliferation through the Wnt signaling pathway.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    PI3K/Akt/mTOR signaling
  • Target
    GSK-3
  • Recptor
    GSK-3
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1139875-74-3
  • Formula Weight
    413.924
  • Molecular Formula
    C20H20ClN5OS
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CN1CCN(CC1)C(=O)C2=C(C=C(C=C2)NC3=NC=CC(=N3)C4=CC=CS4)Cl
  • Chemical Name
    (2-chloro-4-((4-(thiophen-2-yl)pyrimidin-2-yl)amino)phenyl)(4-methylpiperazin-1-yl)methanone

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Wang W, et al. Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1427-32.
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