GSK-3β inhibitor 11( —— )

Catalog No. M35593 CAS No. 536731-65-4

GSK-3β inhibitor 11 (compound 21) is a potent glycogen synthase kinase-3β (GSK-3β) inhibitor with an IC50 of 10.02 μM, demonstrating potential utility in neurodegenerative disease research .

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

GSK-3β inhibitor 11
Note

Research use only, not for human use.
Brief Description

GSK-3β inhibitor 11 (compound 21) is a potent glycogen synthase kinase-3β (GSK-3β) inhibitor with an IC50 of 10.02 μM, demonstrating potential utility in neurodegenerative disease research .
Description

GSK-3β inhibitor 11 (compound 21) is a glycogen synthase kinase-3β (GSK-3β) inhibitor (IC50=10.02 μM). GSK-3β inhibitor 11 can be used in neurodegenerative disease research.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

PI3K/Akt/mTOR signaling
Target

GSK-3
Recptor

GSK-3
Research Area

——
Indication

——

Chemical Information

CAS Number

536731-65-4
Formula Weight

393.42
Molecular Formula

C20H15N3O4S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 20.83 mg/mL (52.95 mM; Ultrasonic (<60°C)
SMILES

COc1cccc(c1)-c1csc(NC(=O)CN2C(=O)c3ccccc3C2=O)n1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Fu G, et al. Pharmacophore Modeling, Ensemble Docking, Virtual Screening, and Biological Evaluation on Glycogen Synthase Kinase-3β. Mol Inform. 2014 Sep;33(9):610-26.?

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