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GSK-3β inhibitor 11
CAS No. 536731-65-4
GSK-3β inhibitor 11( —— )
Catalog No. M35593 CAS No. 536731-65-4
GSK-3β inhibitor 11 (compound 21) is a potent glycogen synthase kinase-3β (GSK-3β) inhibitor with an IC50 of 10.02 μM, demonstrating potential utility in neurodegenerative disease research .
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 39 | In Stock |
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| 5MG | 29 | In Stock |
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| 10MG | 44 | In Stock |
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| 25MG | 91 | In Stock |
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| 50MG | 144 | In Stock |
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| 100MG | 231 | In Stock |
|
| 200MG | 319 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameGSK-3β inhibitor 11
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NoteResearch use only, not for human use.
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Brief DescriptionGSK-3β inhibitor 11 (compound 21) is a potent glycogen synthase kinase-3β (GSK-3β) inhibitor with an IC50 of 10.02 μM, demonstrating potential utility in neurodegenerative disease research .
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DescriptionGSK-3β inhibitor 11 (compound 21) is a glycogen synthase kinase-3β (GSK-3β) inhibitor (IC50=10.02 μM). GSK-3β inhibitor 11 can be used in neurodegenerative disease research.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayPI3K/Akt/mTOR signaling
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TargetGSK-3
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RecptorGSK-3
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Research Area——
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Indication——
Chemical Information
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CAS Number536731-65-4
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Formula Weight393.42
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Molecular FormulaC20H15N3O4S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 20.83 mg/mL (52.95 mM; Ultrasonic (<60°C)
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SMILESCOc1cccc(c1)-c1csc(NC(=O)CN2C(=O)c3ccccc3C2=O)n1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Fu G, et al. Pharmacophore Modeling, Ensemble Docking, Virtual Screening, and Biological Evaluation on Glycogen Synthase Kinase-3β. Mol Inform. 2014 Sep;33(9):610-26.?
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