CYM5442( CYM-5442 | CYM 5442 | CYM5442 )

Catalog No. M10363 CAS No. 1094042-01-9

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

CYM5442
Note

Research use only, not for human use.
Brief Description

CYM5442 is a S1P agonist, target to Sphingosine.
Description

CYM5442 is a S1P agonist, target to Sphingosine.
In Vitro

——
In Vivo

Animal Model:Adult male albino Wistar rats (8-10 weeks old; 180-230 g) infected ocular endothelin-1 (ET-1) Dosage:1 mg/kg Administration:Intraperitoneal injection; daily; for 5 days Result:Visual evoked potentials (VEP) showed preserved visual function. Showed significantly higher retinal ganglion cells (RGCs) numbers.
Synonyms

CYM-5442 | CYM 5442 | CYM5442
Pathway

GPCR/G Protein
Target

S1P Receptor
Recptor

SphK
Research Area

Inflammation/Immunology
Indication

——

CAS Number

1094042-01-9
Formula Weight

409.49
Molecular Formula

C23H27N3O4
Purity

>98% (HPLC)
Solubility

DMSO: > 10 mM
SMILES

CCOC1=CC=C(C2=NC(C3=CC=CC4=C3CCC4NCCO)=NO2)C=C1OCC
Chemical Name

2-((4-(5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl)amino)ethan-1-ol

1.Poti F, et al. Vascul Pharmacol. 2012 Aug 19;57(1):56-64.

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