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Teriflunomide
CAS No. 108605-62-5
Teriflunomide( A77 1726 | HMR 1726 | teriflunomide | Brande name: Aubagio. )
Catalog No. M10335 CAS No. 108605-62-5
Teriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting pyrimidine synthesis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
|
| 50MG | 29 | In Stock |
|
| 100MG | 45 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTeriflunomide
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NoteResearch use only, not for human use.
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Brief DescriptionTeriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting pyrimidine synthesis.
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DescriptionTeriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting pyrimidine synthesis. It is marketed under the name Aubagio and is indicated for the treatment of multiple sclerosis, specifically relapsing forms.
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In Vitro——
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In Vivo——
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SynonymsA77 1726 | HMR 1726 | teriflunomide | Brande name: Aubagio.
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PathwayMetabolic Enzyme/Protease
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TargetDehydrogenase
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RecptorDihydroorotate Dehydrogenase
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Research AreaInflammation/Immunology
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Indication——
Chemical Information
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CAS Number108605-62-5
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Formula Weight270.21
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Molecular FormulaC12H9F3N2O2
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Purity>98% (HPLC)
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SolubilityEthanol: 1 mg/mL ,1; Water: <1 mg/mL (<1 mM); DMSO: 32 mg/mL (118.42 mM)
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SMILESC/C(O)=C(C#N)/C(NC1=CC=C(C(F)(F)F)C=C1)=O
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Chemical Name(Z)-2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide.
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Palmer AM. Curr Opin Investig Drugs. 2010 Nov;11(11):1313-23.
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