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BMP signaling agonist sb4
CAS No. 100874-08-6
BMP signaling agonist sb4( SB 4 | SB4 | SB-4 )
Catalog No. M10057 CAS No. 100874-08-6
BMP signaling agonist sb4 is a small molecule BMP signaling agonist with EC50 of 73.6 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 41 | In Stock |
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| 5MG | 37 | In Stock |
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| 10MG | 52 | In Stock |
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| 25MG | 86 | In Stock |
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| 50MG | 119 | In Stock |
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| 100MG | 183 | In Stock |
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| 200MG | 276 | In Stock |
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| 500MG | 480 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBMP signaling agonist sb4
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NoteResearch use only, not for human use.
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Brief DescriptionBMP signaling agonist sb4 is a small molecule BMP signaling agonist with EC50 of 73.6 nM.
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DescriptionBMP signaling agonist sb4 is a small molecule BMP signaling agonist with EC50 of 73.6 nM, enhances the efficacy of BMPs and activates endogenous BMP4 target genes; increases the phosphorylation of key second messengers (SMADs-1/5/9) and also increased expression of direct target genes (inhibitors of DNA binding, ID1 and ID3) in canonical BMP signaling.
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In Vitro——
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In Vivo——
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SynonymsSB 4 | SB4 | SB-4
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PathwayTGF-beta/Smad
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TargetTGFBR
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RecptorTGFBR
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Research Area——
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Indication——
Chemical Information
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CAS Number100874-08-6
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Formula Weight320.204
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Molecular FormulaC14H10BrNOS
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (312.30 mM)
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SMILESBrC1=CC=C(CSC2=NC3=CC=CC=C3O2)C=C1
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Chemical Name2-((4-bromobenzyl)thio)benzo[d]oxazole
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Bradford STJ, et al. J Biol Chem. 2019 Jan 2. pii: jbc.RA118.006817.
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