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ML-346
CAS No. 100872-83-1
ML-346( ML346 )
Catalog No. M10056 CAS No. 100872-83-1
A novel activator of HSP70 with EC50 of 4.6 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 73 | In Stock |
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| 2MG | 46 | In Stock |
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| 5MG | 73 | In Stock |
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| 10MG | 111 | In Stock |
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| 25MG | 171 | In Stock |
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| 50MG | 268 | In Stock |
|
| 100MG | 419 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 918 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameML-346
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NoteResearch use only, not for human use.
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Brief DescriptionA novel activator of HSP70 with EC50 of 4.6 uM.
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DescriptionA novel activator of HSP70 with EC50 of 4.6 uM; induces HSF-1-dependent chaperone expression and restores protein folding in conformational disease models, which are mediated by novel mechanisms involving FOXO, HSF-1, and Nfr-2.
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In Vitro——
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In Vivo——
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SynonymsML346
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetHSP
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RecptorHSP70
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number100872-83-1
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Formula Weight272.2561
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Molecular FormulaC14H12N2O4
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 29 mg/mL
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SMILESO=C(NC(NC/1=O)=O)C1=C\C=C\C2=CC=C(OC)C=C2
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Chemical Name2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[3-(4-methoxyphenyl)-2-propen-1-ylidene]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Calamini B, et al. Probe Reports from the NIH Molecular Libraries Program.
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