Home - Products - Membrane Transporter/Ion Channel - iGluR - LY450108

LY450108

CAS No. 376594-67-1

LY450108( —— )

Catalog No. M29625 CAS No. 376594-67-1

LY450108 is a potentiator of the AMPA receptor that can be used in Parkinson's disease studies.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	160	Get Quote
10MG	260	Get Quote
25MG	465	Get Quote
50MG	673	Get Quote
100MG	945	Get Quote
500MG	1881	Get Quote
1G	Get Quote	Get Quote

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

LY450108
Note

Research use only, not for human use.
Brief Description

LY450108 is a potentiator of the AMPA receptor that can be used in Parkinson's disease studies.
Description

LY450108 is a potentiator of the AMPA receptor that can be used in Parkinson's disease studies.
In Vitro

AMPA receptors mediate most of the excitatory neurotransmission and play a key role in synaptic plasticity in the mammalian central nervous system (CNS). Recent evidence has shown that in addition to modulating fast synaptic plasticity and memory processes, AMPA receptor potentiators alter downstream signalling pathways and may thereby have utility in other CNS disorders.
In Vivo

——
Synonyms

——
Pathway

Membrane Transporter/Ion Channel
Target

iGluR
Recptor

iGluR
Research Area

——
Indication

——

Chemical Information

CAS Number

376594-67-1
Formula Weight

396.45
Molecular Formula

C19H22F2N2O3S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : ≥ 50 mg/mL (126.12 mM)
SMILES

CC(C)S(NC[C@H](C)c(cc1)ccc1NC(c1cc(F)cc(F)c1)=O)(=O)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

related products

Rislenemdaz mesylate

Rislenemdaz (MK 0657;CERC 301) is a potent, orally bioavailable, brain‐penetrant, NR2B-selective NMDA receptor (GluN2B) antagonist with Ki and IC 50 of 8.1 nM and 3.6 nM respectively.
CNQX disodium

CNQX disodium is a competitive non-NMDA receptor antagonist and competitive AMPA/kainate receptor antagonist in neuronal cultures.
PEPA

PEPA is an allosteric AMPA receptors modulator; binds to the GluA2o and GluA3o LBDs and can be utilized as an indicator of AMPA receptor heterogeneity.

Sign In Join Free