LEM-14-1189( —— )

Catalog No. M17069 CAS No. ——

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

LEM-14-1189
Note

Research use only, not for human use.
Brief Description

LEM-14-1189 is a LEM-14 derivative that differentially inhibits the NSDs.
Description

LEM-14-1189 is a LEM-14 derivative that differentially inhibits the NSDs with in vitro IC50 of 418 μM (NSD1), IC50 of 111 μM (NSD2) and IC50 of 60 μM (NSD3).
In Vitro

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In Vivo

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Synonyms

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Pathway

Chromatin/Epigenetic
Target

HMTase
Recptor

HMTase
Research Area

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Indication

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CAS Number

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Formula Weight

682.814
Molecular Formula

C35H34N6O5S2
Purity

>98% (HPLC)
Solubility

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SMILES

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Chemical Name

N-(3-(bis((4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)methyl)amino)propyl)-1-oxo-1H-isochromene-3-carboxamide

1. Shen Y, et al. Biochem Biophys Res Commun. 2018 Nov 21. pii: S0006-291X(18)32443-4.

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