Iberdomide

CAS No. 1323403-33-3

Iberdomide( CC-220 )

Catalog No. M21067 CAS No. 1323403-33-3

Iberdomide is a modulator of cereblon( IC50 value of 60 nM in a competitive TR-FRET assay).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 50 Get Quote
5MG 87 Get Quote
10MG 155 Get Quote
25MG 309 Get Quote
50MG 551 Get Quote
100MG 869 Get Quote
200MG 1161 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Iberdomide
  • Note
    Research use only, not for human use.
  • Brief Description
    Iberdomide is a modulator of cereblon( IC50 value of 60 nM in a competitive TR-FRET assay).
  • Description
    Iberdomide is a modulator of cereblon( IC50 value of 60 nM in a competitive TR-FRET assay).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    CC-220
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    Apoptosis
  • Research Area
    Metabolic Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    1323403-33-3
  • Formula Weight
    449.5
  • Molecular Formula
    C25H27N3O5
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:30 mg/mL (66.74 mM)
  • SMILES
    O=C1CCC(N2Cc3c(OCc4ccc(CN5CCOCC5)cc4)cccc3C2=O)C(=O)N1
  • Chemical Name
    (S)-3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-26-dione

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Matyskiela M E Zhang W Man H W et al. A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos[J]. Journal of Medicinal Chemistry 2017:acs.jmedchem.6b01921.
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