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IVA-337
CAS No. 927961-18-0
IVA-337( Lanifibranor | IVA337 )
Catalog No. M16646 CAS No. 927961-18-0
IVA-337 (Lanifibranor, IVA337)) is a potent, pan PPAR agonist with EC50 of 0.92 uM, 0.53 uM and 0.18 uM for human PPARα, PPARδ and PPARγ respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 31 | In Stock |
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| 5MG | 50 | In Stock |
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| 10MG | 87 | In Stock |
|
| 25MG | 176 | In Stock |
|
| 50MG | 322 | In Stock |
|
| 100MG | 485 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameIVA-337
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NoteResearch use only, not for human use.
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Brief DescriptionIVA-337 (Lanifibranor, IVA337)) is a potent, pan PPAR agonist with EC50 of 0.92 uM, 0.53 uM and 0.18 uM for human PPARα, PPARδ and PPARγ respectively.
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DescriptionIVA-337 (Lanifibranor, IVA337)) is a potent, pan PPAR agonist with EC50 of 0.92 uM, 0.53 uM and 0.18 uM for human PPARα, PPARδ and PPARγ respectively; reduces skin fibrosis in the mouse, and suppresses inflammation in vivo.Steatohepatitis,Phase 2 Clinical.
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In Vitro——
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In Vivo——
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SynonymsLanifibranor | IVA337
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PathwayMetabolic Enzyme/Protease
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TargetPPAR
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RecptorPPAR
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Research AreaOther Indications
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IndicationSteatohepatitis
Chemical Information
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CAS Number927961-18-0
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Formula Weight434.909
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Molecular FormulaC19H15ClN2O4S2
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Purity>98% (HPLC)
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SolubilityDMSO : 100 mg/mL 229.93 mM
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SMILESO=C(O)CCCC(N1S(=O)(C2=CC=C3N=CSC3=C2)=O)=CC4=C1C=CC(Cl)=C4
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Chemical Name4-(1-(1,3-Benzothiazol-6-ylsulfonyl)-5-chloro-indol-2-yl)butanoic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Ruzehaji N, et al. Ann Rheum Dis. 2016 Dec;75(12):2175-2183.
2. Avouac J, et al. Ann Rheum Dis. 2017 Aug 11. pii: annrheumdis-2016-210821.
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