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I942
CAS No. 868145-09-9
I942( —— )
Catalog No. M33988 CAS No. 868145-09-9
I942 is a novel, selective ACyclic nucleotide (NCN) EPAC1 agonist that activates exchange proteins to regulate inflammatory gene expression in human umbilical blood tubes and inhibit pro-inflammatory cytokine signaling associated with cardiovascular disease.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 146 | Get Quote |
|
| 5MG | 227 | Get Quote |
|
| 10MG | 370 | Get Quote |
|
| 25MG | 587 | Get Quote |
|
| 50MG | 811 | Get Quote |
|
| 100MG | 1071 | Get Quote |
|
| 500MG | 2187 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameI942
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NoteResearch use only, not for human use.
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Brief DescriptionI942 is a novel, selective ACyclic nucleotide (NCN) EPAC1 agonist that activates exchange proteins to regulate inflammatory gene expression in human umbilical blood tubes and inhibit pro-inflammatory cytokine signaling associated with cardiovascular disease.
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DescriptionI942 is a first in class, selective non-cyclic nucleotide (NCN) EPAC1 agonist. I942 can attenuate proinflammatory cytokine signalling normally associated with cardiovascular diseases.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetcAMP
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RecptorcAMP
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Research Area——
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Indication——
Chemical Information
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CAS Number868145-09-9
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Formula Weight369.43
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Molecular FormulaC20H19NO4S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (676.72 mM; Ultrasonic )
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SMILESO(CC(NS(=O)(=O)C1=C(C)C=C(C)C=C1)=O)C2=CC3=C(C=C2)C=CC=C3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Graeme Barker, et al. The Potential of a Novel Class of EPAC-Selective Agonists to Combat Cardiovascular Inflammation. J Cardiovasc Dev Dis. 2017 Dec 5;4(4):22.?
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