Galloflavin( —— )

Catalog No. M24558 CAS No. 568-80-9

Galloflavin inhibits both the A and B isoforms of lactate dehydrogenase with Ki of 5.46 μM and 15.06 μM, respectively.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Galloflavin
Note

Research use only, not for human use.
Brief Description

Galloflavin inhibits both the A and B isoforms of lactate dehydrogenase with Ki of 5.46 μM and 15.06 μM, respectively.
Description

Galloflavin inhibits both the A and B isoforms of lactate dehydrogenase with Ki of 5.46 μM and 15.06 μM, respectively. Galloflavin is also a potential anticancer agent.
In Vitro

Galloflavin effectively inhibits cell growth in endometrial cancer cell lines and primary cultures of human endometrial cancer through its involvement in multiple signaling pathways that regulate metabolism, cell cycle, apoptosis, cell stress and metastasis.
In Vivo

——
Synonyms

——
Pathway

Metabolic Enzyme/Protease
Target

Dehydrogenase
Recptor

LDH
Research Area

——
Indication

——

Chemical Information

CAS Number

568-80-9
Formula Weight

278.17
Molecular Formula

C12H6O8
Purity

>98% (HPLC)
Solubility

DMSO:1.9 mg/ml (6.83 mM)
SMILES

OC(C=C1OC(C2=CC3=O)=O)=C(O)OC1=C2C(O)=C3O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Manerba M, Vettraino M, Fiume L, Di Stefano G, Sartini A, Giacomini E, Buonfiglio R, Roberti M, Recanatini M. Galloflavin (CAS 568-80-9): a novel inhibitor of lactate dehydrogenase. ChemMedChem. 2012 Feb 6;7(2):311-7.

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