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GLX351322
CAS No. 835598-94-2
GLX351322( —— )
Catalog No. M21200 CAS No. 835598-94-2
GLX351322 is NADPH Oxidase 4 Inhibitor with IC50 of 5 μM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 38 | Get Quote |
|
| 5MG | 61 | Get Quote |
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| 10MG | 101 | Get Quote |
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| 25MG | 230 | Get Quote |
|
| 50MG | 392 | Get Quote |
|
| 100MG | 582 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameGLX351322
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NoteResearch use only, not for human use.
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Brief DescriptionGLX351322 is NADPH Oxidase 4 Inhibitor with IC50 of 5 μM.
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DescriptionGLX351322 is NADPH Oxidase 4 Inhibitor with IC50 of 5 μM.
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In VitroGLX351322 is an inhibitor of NADPH oxidase 4, and inhibits hydrogen peroxide production from NOX4-overexpressing cells with an IC50 of 5 μM. GLX351322 shows weak activity against NOX2 in hPBMC cells (IC50, 40 μM).
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In VivoGLX351322 (3.8 mg/kg/day, p.o.) ameliorates HFD-induced hyperglycemia in mice.
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Synonyms——
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PathwayMembrane Transporter/Ion Channel
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TargetNADPH
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RecptorNOX4
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Research Area——
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Indication——
Chemical Information
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CAS Number835598-94-2
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Formula Weight431.5
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Molecular FormulaC21H25N3O5S
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Purity>98% (HPLC)
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SolubilityDMSO:20 mg/mL (46.35 mM; Need ultrasonic)
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SMILESCCOC(=O)c1c(NC(=O)CN2CCN(C(=O)c3ccco3)CC2)sc2c1CCC2
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Chemical NameEthyl 2-[[2-[4-(furan-2-carbonyl)piperazin-1-yl]acetyl]amino]-56-dihydro-4H-cyclopenta-[b]thiophene-3-carboxylate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Anvari Ebrahim Wikstr?m Per Walum Eriket al. The novel NADPH oxidase 4 inhibitor GLX351322 counteracts glucose intolerance in high-fat diet-treated C57BL/6 mice[J]. Free Radical Research 49(11):1-32.
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