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Fluorobexarotene
CAS No. 1190848-23-7
Fluorobexarotene( —— )
Catalog No. M32926 CAS No. 1190848-23-7
Fluorobexarotene possesses an apparent RXR binding affinity that is 75% greater than Bexarotene.?
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 278 | Get Quote |
|
| 5MG | 440 | Get Quote |
|
| 10MG | 649 | Get Quote |
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| 25MG | 984 | Get Quote |
|
| 50MG | 1334 | Get Quote |
|
| 100MG | 1755 | Get Quote |
|
| 500MG | 3501 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameFluorobexarotene
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NoteResearch use only, not for human use.
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Brief DescriptionFluorobexarotene possesses an apparent RXR binding affinity that is 75% greater than Bexarotene.?
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DescriptionFluorobexarotene (compound 20) is a potent retinoid-X-receptor (RXR) agonist, with a Ki value of 12 nM and an EC50 value of 43 nM for RXRα receptor. Fluorobexarotene possesses an apparent RXR binding affinity that is 75% greater than Bexarotene.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetRetinoid Receptor
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RecptorRetinoid Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number1190848-23-7
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Formula Weight366.47
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Molecular FormulaC24H27FO2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 36 mg/mL (98.23 mM )
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SMILESCC1=CC2=C(C=C1C(=C)C1=CC(F)=C(C=C1)C(O)=O)C(C)(C)CCC2(C)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Wagner CE, et al. Modeling, synthesis and biological evaluation of potential retinoid X receptor (RXR) selective agonists: novel analogues of 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic acid (bexarotene). J Med Chem. 2009 Oct?
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