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Fagomine
CAS No. 53185-12-9
Fagomine( —— )
Catalog No. M37948 CAS No. 53185-12-9
Fagomine (D-Fagomine) is a mild glycosidase inhibitor, an analog of 1-deoxynojirimycin (DNJ) with hypoglycemic activity, and Fagomine reduces intracellular reactive oxygen species (ROS) production and malondialdehyde (MDA) levels.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 302 | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameFagomine
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NoteResearch use only, not for human use.
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Brief DescriptionFagomine (D-Fagomine) is a mild glycosidase inhibitor, an analog of 1-deoxynojirimycin (DNJ) with hypoglycemic activity, and Fagomine reduces intracellular reactive oxygen species (ROS) production and malondialdehyde (MDA) levels.
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DescriptionFagomine is a mild glycosidase inhibitor. The Ki of the iminosugar Fagomine is 4.8 μM, 39 μM, and 70 μM for Amyloglucosidase (A.niger), β-Glucosidase (bovine), and Isomaltase (yeast), respectively.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayImmunology/Inflammation
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TargetROS
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RecptorROS | glycosidase
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Research Area——
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Indication——
Chemical Information
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CAS Number53185-12-9
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Formula Weight147.17
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Molecular FormulaC6H13NO3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?H2O : ≥ 36 mg/mL (244.62 mM)
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SMILESOC[C@H]1NCC[C@@H](O)[C@@H]1O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Mena-Barragán T, et al. Inhibitor versus chaperone behaviour of d-fagomine, DAB and LAB sp2-iminosugar conjugates againstglycosidases: A structure-activity relationship study in Gaucher fibroblasts. Eur J Med Chem. 2015 Aug 31. pii: S0223-5234(15)30222-1.?
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