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FAK-IN-14
CAS No. 2766666-22-0
FAK-IN-14( —— )
Catalog No. M37125 CAS No. 2766666-22-0
FAK-IN-14 is a highly effective focal adhesion kinase (FAK) inhibitor that induces apoptosis and cell cycle arrest.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 67 | Get Quote |
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| 5MG | 93 | Get Quote |
|
| 10MG | 155 | Get Quote |
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| 25MG | 254 | Get Quote |
|
| 50MG | 365 | Get Quote |
|
| 100MG | 538 | Get Quote |
|
| 500MG | 1134 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameFAK-IN-14
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NoteResearch use only, not for human use.
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Brief DescriptionFAK-IN-14 is a highly effective focal adhesion kinase (FAK) inhibitor that induces apoptosis and cell cycle arrest.
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DescriptionFAK-IN-14 (compound 8d) is a focal adhesion kinase(FAK) inhibitor with an IC50 value of 0.2438 nM. FAK-IN-14 induces U87-MG cell early apoptosis and arrest the cell at the G2/M phase.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetFAK
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RecptorFAK | FGFR | PYK2 | mTOR | MEK | Akt | c-Kit
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Research Area——
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Indication——
Chemical Information
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CAS Number2766666-22-0
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Formula Weight502.43
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Molecular FormulaC21H24BrN7OS
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(NC)C=1SC=CC1NC2=NC(=NC=C2Br)NC3=CC=C(C=C3)N4CCN(C)CC4
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Zhiwu Long, et al. Design, synthesis and biological evaluation of 4-arylamino-pyrimidine derivatives as focal adhesion kinase inhibitors. Bioorg Chem. 2023.?
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