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Etidronate
CAS No. 2809-21-4
Etidronate( —— )
Catalog No. M13855 CAS No. 2809-21-4
Etidronate (Didronel) is a human protein tyrosine phosphatase inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 500MG | 37 | In Stock |
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| 1G | 59 | In Stock |
|
Biological Information
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Product NameEtidronate
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NoteResearch use only, not for human use.
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Brief DescriptionEtidronate (Didronel) is a human protein tyrosine phosphatase inhibitor.
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DescriptionEtidronate (Didronel) is a human protein tyrosine phosphatase inhibitor.(In Vitro):Etidronic acid (Etidronate) (10 mM, 24 h) shows cytotoxicity, causes a decrease in the S-phase population and an increase in the G2/M population, induces p53 mutation in MCF-7 cells.Etidronic acid (100 nM, 24 h) induces osteoclast apoptosis, which displays characteristics of apoptosis, including chromatin condensation and changed cellular and nuclear morphology, detected by fluorescence microscopy.
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In VitroEtidronic acid (Etidronate) (10 mM, 24 h) shows cytotoxicity, causes a decrease in the S-phase population and an increase in the G2/M population, induces p53 mutation in MCF-7 cells.Etidronic acid (100 nM, 24 h) induces osteoclast apoptosis, which displays characteristics of apoptosis, including chromatin condensation and changed cellular and nuclear morphology, detected by fluorescence microscopy.
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In Vivo——
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Synonyms——
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PathwayMicrobiology/Virology
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TargetHBV
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RecptorHAP| PTPase S| V-type proton ATPase catalytic subunit
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Research AreaOther Indications
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Indication——
Chemical Information
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CAS Number2809-21-4
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Formula Weight206.03
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Molecular FormulaC2H8O7P2
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Purity>98% (HPLC)
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SolubilityWater: 41 mg/mL (199.0 mM)
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SMILESCC(O)(P(=O)(O)O)P(=O)(O)O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Grases F, et al. Circ J. 2007 Jul;71(7):1152-6.
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