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Eliprodil
CAS No. 119431-25-3
Eliprodil( SL-820715 )
Catalog No. M10679 CAS No. 119431-25-3
Eliprodil (SL-820715) is a non-competitive NR2B-NMDA receptor antagonist, less potent for NR2A- and NR2C-containing receptors (IC50>100 uM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 46 | In Stock |
|
| 10MG | 83 | In Stock |
|
| 25MG | 159 | In Stock |
|
| 50MG | 304 | In Stock |
|
| 100MG | 462 | In Stock |
|
| 500MG | 972 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameEliprodil
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NoteResearch use only, not for human use.
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Brief DescriptionEliprodil (SL-820715) is a non-competitive NR2B-NMDA receptor antagonist, less potent for NR2A- and NR2C-containing receptors (IC50>100 uM).
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DescriptionEliprodil (SL-820715) is a non-competitive NR2B-NMDA receptor antagonist, less potent for NR2A- and NR2C-containing receptors (IC50>100 uM); inhibits [3H]norepinephrine release from cortical and hippocampal slices but enhances the basal efflux of endogenous and tritiated dopamine from striatal slices, also blocks the uptake of [3H]dopamine into striatal synaptosomes with IC50 of 1.5 uM; reduces the volume of infarction in models of focal cerebral ischemia.Stroke Phase 3 Discontinued.
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In Vitro——
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In Vivo——
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SynonymsSL-820715
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PathwayMembrane Transporter/Ion Channel
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TargetiGluR
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RecptorNR2B-NMDA
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Research AreaNeurological Disease
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IndicationStroke
Chemical Information
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CAS Number119431-25-3
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Formula Weight347.8541
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Molecular FormulaC20H23ClFNO
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESOC(C1=CC=C(Cl)C=C1)CN2CCC(CC3=CC=C(F)C=C3)CC2
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Chemical Name1-Piperidineethanol, α-(4-chlorophenyl)-4-[(4-fluorophenyl)methyl]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Woodward JJ, et al. Eur J Pharmacol. 1992 Jan 21;210(3):265-70.
2. Carter CJ, et al. J Pharmacol Exp Ther. 1990 May;253(2):475-82.
3. Carter C, et al. Eur J Pharmacol. 1989 May 30;164(3):611-2.
4. Bath CP, et al. Eur J Pharmacol. 1996 Mar 28;299(1-3):103-12.
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