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Elexacaftor
CAS No. 2216712-66-0
Elexacaftor( VX-445 )
Catalog No. M24000 CAS No. 2216712-66-0
Elexacaftor is a modulator of cystic fibrosis transmembrane conductance regulator (CFTR) and it also facilitates the processing and trafficking of CFTR to increase the amount of CFTR at the cell surface.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 282 | In Stock |
|
| 10MG | 444 | In Stock |
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| 25MG | 731 | In Stock |
|
| 50MG | 1017 | In Stock |
|
| 100MG | 1368 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameElexacaftor
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NoteResearch use only, not for human use.
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Brief DescriptionElexacaftor is a modulator of cystic fibrosis transmembrane conductance regulator (CFTR) and it also facilitates the processing and trafficking of CFTR to increase the amount of CFTR at the cell surface.
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DescriptionElexacaftor is a modulator of cystic fibrosis transmembrane conductance regulator (CFTR) and it also facilitates the processing and trafficking of CFTR to increase the amount of CFTR at the cell surface.
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In Vitro——
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In Vivo——
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SynonymsVX-445
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PathwayApoptosis
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TargetCFTR
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RecptorCFTR
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Research Area——
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Indication——
Chemical Information
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CAS Number2216712-66-0
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Formula Weight597.65
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Molecular FormulaC26H34F3N7O4S
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Purity>98% (HPLC)
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SolubilityDMSO:125 mg/mL (209.15 mM; Need ultrasonic)
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SMILESC[C@H]1CC(N(C1)C2=C(C=CC(=N2)N3C=CC(=N3)OCC(C)(C)C(F)(F)F)C(=O)NS(=O)(=O)C4=CN(N=C4C)C)(C)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Alexander Russell Abela, et al. MODULATOR OF THE CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR , PHARMACEUTICAL COMPOSITIONS , METHODS OF TREATMENT , AND PROCESS FOR MAKING THE MODULATOR. US 20180162839 A1.
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