EM-12

CAS No. 26581-81-7

EM-12( —— )

Catalog No. M35279 CAS No. 26581-81-7

2-(2,6-Dioxopiperidin-3-yl)phthalimidine (EM-12 (2-(2,6-Dioxopiperidin-3-yl)phthalimidine)) is a teratogenic Thalidomide analogue that is more active and significantly more stable against hydrolysis than Thalidomide, enhancing 1,2-dimethylhydrazine-induced rat colon adenocarcinomas .

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 29 Get Quote
10MG 47 Get Quote
25MG 90 Get Quote
50MG 136 Get Quote
100MG 198 Get Quote
200MG 293 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    EM-12
  • Note
    Research use only, not for human use.
  • Brief Description
    2-(2,6-Dioxopiperidin-3-yl)phthalimidine (EM-12 (2-(2,6-Dioxopiperidin-3-yl)phthalimidine)) is a teratogenic Thalidomide analogue that is more active and significantly more stable against hydrolysis than Thalidomide, enhancing 1,2-dimethylhydrazine-induced rat colon adenocarcinomas .
  • Description
    2-(2,6-Dioxopiperidin-3-yl)phthalimidine (EM-12), a teratogenic Thalidomide analogue, is more active than Thalidomide and is much more stable for hydrolysis. 2-(2,6-Dioxopiperidin-3-yl)phthalimidineenhances 1,2-dimethylhydrazine-induction of rat colon adenocarcinomas.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    26581-81-7
  • Formula Weight
    244.25
  • Molecular Formula
    C13H12N2O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (511.77 mM; Ultrasonic )
  • SMILES
    O=C1N(CC=2C1=CC=CC2)C3C(=O)NC(=O)CC3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Merker HJ, et al. Embryotoxic effects of thalidomide-derivatives in the non-human primate Callithrix jacchus. I. Effects of 3-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-dioxopiperidine (EM12) on skeletal development. Arch Toxicol. 1988;61(3):165-179.?
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