Deserpidine( Harmonyl )

Catalog No. M21425 CAS No. 131-01-1

Deserpidine is only found in individuals that have used or taken this drug. It is an ester alkaloid drug isolated from Rauwolfia canescens (family Apocynaceae) with antipsychotic and antihypertensive properties that has been used for the control of high blood pressure and for the relief of psychotic behavior.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	120	Get Quote
10MG	200	Get Quote
25MG	374	Get Quote
50MG	530	Get Quote
100MG	770	Get Quote
500MG	1521	Get Quote
1G	Get Quote	Get Quote

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Biological Information

Product Name

Deserpidine
Note

Research use only, not for human use.
Brief Description

Deserpidine is only found in individuals that have used or taken this drug. It is an ester alkaloid drug isolated from Rauwolfia canescens (family Apocynaceae) with antipsychotic and antihypertensive properties that has been used for the control of high blood pressure and for the relief of psychotic behavior.
Description

Deserpidine is only found in individuals that have used or taken this drug. It is an ester alkaloid drug isolated from Rauwolfia canescens (family Apocynaceae) with antipsychotic and antihypertensive properties that has been used for the control of high blood pressure and for the relief of psychotic behavior.Deserpidine's mechanism of action is through inhibition of the ATP/Mg2+ pump responsible for the sequestering of neurotransmitters into storage vesicles located in the presynaptic neuron. Deserpidine is a competitive angiotensin converting enzyme (ACE) inhibitor. Deserpidine also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex.(In Vitro):Deserpidine is an effective ganglionic blocking agent, which differs from Reserpine only by the absence of a methoxy group at C-11. Deserpidine has been used in the treatment of hypertension and psychosis. In addition, Deserpidine appears to act as a controller of other cardiac disorders.
In Vitro

Deserpidine is an effective ganglionic blocking agent, which differs from Reserpine only by the absence of a methoxy group at C-11. Deserpidine has been used in the treatment of hypertension and psychosis. In addition, Deserpidine appears to act as a controller of other cardiac disorders.
In Vivo

——
Synonyms

Harmonyl
Pathway

Endocrinology/Hormones
Target

RAAS
Recptor

ACE
Research Area

Cardiovascular Disease
Indication

hypertension

Chemical Information

CAS Number

131-01-1
Formula Weight

578.7
Molecular Formula

C32H38N2O8
Purity

>98% (HPLC)
Solubility

DMSO:1 mg/mL (172.82 mM)
SMILES

CO[C@H]1[C@@H](C[C@@H]2CN3CCC4=C([C@H]3C[C@@H]2[C@@H]1C(=O)OC)NC5=CC=CC=C45)OC(=O)C6=CC(=C(C(=C6)OC)OC)OC
Chemical Name

methyl (1R15S17R18R19S20S)-18-methoxy-17-(345-trimethoxybenzoyloxy)-313-diazapentacyclo[11.8.0.0210.049.01520]henicosa-2(10)468-tetraene-19-carboxylate