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Delamanid

CAS No. 681492-22-8

Delamanid( OPC67683 | OPC-67683 | OPC 67683 )

Catalog No. M15601 CAS No. 681492-22-8

A mycolic acid biosynthesis inhibitor found to be free of mutagenicity and to possess highly potent activity against tuberculosis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 58 In Stock
25MG 113 In Stock
50MG 203 In Stock
100MG 329 In Stock
500MG 770 In Stock
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Biological Information

  • Product Name
    Delamanid
  • Note
    Research use only, not for human use.
  • Brief Description
    A mycolic acid biosynthesis inhibitor found to be free of mutagenicity and to possess highly potent activity against tuberculosis.
  • Description
    A mycolic acid biosynthesis inhibitor found to be free of mutagenicity and to possess highly potent activity against tuberculosis, including MDR-TB; shows MIC of 0.006-0.024 ug/mL in vitro and highly effective therapeutic activity at low doses in vivo.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    OPC67683 | OPC-67683 | OPC 67683
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antifection
  • Research Area
    Infection
  • Indication
    ——

Chemical Information

  • CAS Number
    681492-22-8
  • Formula Weight
    534.4844
  • Molecular Formula
    C25H25F3N4O6
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 30 mg/mL
  • SMILES
    FC(F)(F)OC1=CC=C(OC2CCN(C3=CC=C(OC[C@@]4(C)CN5C(O4)=NC([N+]([O-])=O)=C5)C=C3)CC2)C=C1
  • Chemical Name
    Imidazo[2,1-b]oxazole, 2,3-dihydro-2-methyl-6-nitro-2-[[4-[4-[4-(trifluoromethoxy)phenoxy]-1-piperidinyl]phenoxy]methyl]-, (2R)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Matsumoto M, et al. PLoS Med. 2006 Nov;3(11):e466. 2. Li X, et al. Bioorg Med Chem Lett. 2008 Apr 1;18(7):2256-62. 3. Hurdle JG, et al. J Antimicrob Chemother. 2008 Nov;62(5):1037-45.
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