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Home - Products - Metabolic Enzyme/Protease - Dehydrogenase - DHODH-IN-16

DHODH-IN-16

CAS No. 2511248-11-4

DHODH-IN-16( —— )

Catalog No. M28280 CAS No. 2511248-11-4

DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    DHODH-IN-16
  • Note
    Research use only, not for human use.
  • Brief Description
    DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human).
  • Description
    DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human).(In Vitro):DHODH-IN-16 inhibited the growth of MOLM-13 cells effectively (IC50 = 0.2 nM) .
  • In Vitro
    DHODH-IN-16 (Example 22) potently inhibits the growth of MOLM-13 cells with an IC50 of 0.2 nM.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Dehydrogenase
  • Recptor
    TNF-α
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2511248-11-4
  • Formula Weight
    436.48
  • Molecular Formula
    C24H25FN4O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (229.11 mM)
  • SMILES
    CCN(C(CO)=NN1c(cc(C(C(C)C)=CN(c2c(C)cccc2)C2=O)c2c2)c2F)C1=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Deng X, et al. Design, Synthesis, and Evaluation of Dihydrobenzo[cd]indole-6-sulfonamide as TNF-α Inhibitors. Front Chem. 2018 Apr 4;6:98.
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