Corr4A
CAS No. 421580-53-2
Corr4A( Corr 4A )
Catalog No. M14435 CAS No. 421580-53-2
A small molecule corrector of ΔF508-CFTR with IC50 of 6.0 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 435 | Get Quote |
|
| 50MG | 1341 | Get Quote |
|
| 100MG | 1773 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameCorr4A
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NoteResearch use only, not for human use.
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Brief DescriptionA small molecule corrector of ΔF508-CFTR with IC50 of 6.0 uM.
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DescriptionA small molecule corrector of ΔF508-CFTR with IC50 of 6.0 uM.
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In Vitro——
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In Vivo——
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SynonymsCorr 4A
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PathwayApoptosis
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TargetCFTR
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RecptorCFTR
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Research Area——
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Indication——
Chemical Information
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CAS Number421580-53-2
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Formula Weight456.963
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Molecular FormulaC21H17ClN4O2S2
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Purity>98% (HPLC)
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Solubility——
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SMILESCC1=C(C2=CSC(NC3=CC(Cl)=CC=C3OC)=N2)SC(NC(C4=CC=CC=C4)=O)=N1
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Chemical NameN-[2-(5-chloro-2-methoxy-phenylamino)-4'-methyl-[4,5']bithiazolyl-2'-yl]-benzamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Boinot C, et al. J Pharmacol Exp Ther. 2014 Sep;350(3):624-34.
2. Talebian L, et al. Cell Physiol Biochem. 2009;23(1-3):199-204.
3. Coffman KC, et al. J Med Chem. 2014 Aug 14;57(15):6729-38.
4. Pedemonte N, et al. Mol Pharmacol. 2005 Dec;68(6):1736-46.
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