Corr4A

CAS No. 421580-53-2

Corr4A( Corr 4A )

Catalog No. M14435 CAS No. 421580-53-2

A small molecule corrector of ΔF508-CFTR with IC50 of 6.0 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Corr4A
  • Note
    Research use only, not for human use.
  • Brief Description
    A small molecule corrector of ΔF508-CFTR with IC50 of 6.0 uM.
  • Description
    A small molecule corrector of ΔF508-CFTR with IC50 of 6.0 uM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Corr 4A
  • Pathway
    Apoptosis
  • Target
    CFTR
  • Recptor
    CFTR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    421580-53-2
  • Formula Weight
    456.963
  • Molecular Formula
    C21H17ClN4O2S2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC1=C(C2=CSC(NC3=CC(Cl)=CC=C3OC)=N2)SC(NC(C4=CC=CC=C4)=O)=N1
  • Chemical Name
    N-[2-(5-chloro-2-methoxy-phenylamino)-4'-methyl-[4,5']bithiazolyl-2'-yl]-benzamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Boinot C, et al. J Pharmacol Exp Ther. 2014 Sep;350(3):624-34. 2. Talebian L, et al. Cell Physiol Biochem. 2009;23(1-3):199-204. 3. Coffman KC, et al. J Med Chem. 2014 Aug 14;57(15):6729-38. 4. Pedemonte N, et al. Mol Pharmacol. 2005 Dec;68(6):1736-46.
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