CVT-11127

CAS No. 1018674-83-3

CVT-11127( —— )

Catalog No. M23225 CAS No. 1018674-83-3

CVT-11127 is an StearoylCoA Desaturase-1 (SCD1) inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 177 In Stock
10MG 312 In Stock
25MG 530 In Stock
50MG 758 In Stock
100MG 1044 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    CVT-11127
  • Note
    Research use only, not for human use.
  • Brief Description
    CVT-11127 is an StearoylCoA Desaturase-1 (SCD1) inhibitor.
  • Description
    CVT-11127 is an StearoylCoA Desaturase-1 (SCD1) inhibitor.
  • In Vitro
    CVT-11127 (1 μM, 48 h) shows antiproliferation activity in H460 cells.CVT-11127 (1 μM, 48 h) decreases the the population of cells in S-phase by 75%.CVT-11127 (1 μM, 48 h) induces apoposis in H460 cells.CVT-11127 (1, 2 μM) inhibitors the SCD (stearoylCoA desaturase) activity in H460 cells. Cell Proliferation Assay Cell Line:H460 cells Concentration:1 μM Incubation Time:48 h Result:Showed antiproliferation activity.Cell Cycle Analysis Cell Line:H460 cells Concentration:1 μM Incubation Time:48 h Result:Decreased the the population of cells in S-phase by 75%.Apoptosis Analysis Cell Line:H460 cells Concentration:1 μM Incubation Time:24 h Result:Induced apoposis H460 cells.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Dehydrogenase
  • Recptor
    SCD1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1018674-83-3
  • Formula Weight
    512.39
  • Molecular Formula
    C25H23Cl2N5O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:5 mM
  • SMILES
    CC(=O)NCCN1C2=C(C=CC(=N2)NCC3=CC(=C(C=C3)Cl)Cl)N=C(C1=O)C4=CC=C(C=C4)OC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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