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Home - Products - Chromatin/Epigenetic - Epigenetic Reader Domain - CTB

CTB

CAS No. 451491-47-7

CTB( Cholera Toxin B subunit )

Catalog No. M28749 CAS No. 451491-47-7

CTB (Cholera Toxin B subunit) is an activator of p300 histone acetyltransferase and induces apoptosis in MCF-7 cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    CTB
  • Note
    Research use only, not for human use.
  • Brief Description
    CTB (Cholera Toxin B subunit) is an activator of p300 histone acetyltransferase and induces apoptosis in MCF-7 cells.
  • Description
    CTB (Cholera Toxin B subunit) is an activator of p300 histone acetyltransferase and induces apoptosis in MCF-7 cells.(In Vitro):dose-dependent.
  • In Vitro
    Cell Viability Assay Cell Line:MCF-7 cell Concentration:0-200 μM Incubation Time:24 hours Result:Inhibit viability with an IC50 of 85.43 μM.Apoptosis Analysis Cell Line:MCF-7 cell Concentration:85.43 μM Incubation Time:24, 48 and 72 h Result:Iinduced time-dependence apoptosis.
  • In Vivo
    ——
  • Synonyms
    Cholera Toxin B subunit
  • Pathway
    Chromatin/Epigenetic
  • Target
    Epigenetic Reader Domain
  • Recptor
    D2 receptor|5-HT2A
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    451491-47-7
  • Formula Weight
    686.45
  • Molecular Formula
    C32H25Cl2F6N2O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (290.93 mM)
  • SMILES
    CCOc(cccc1)c1C(Nc(cc1)cc(C(F)(F)F)c1Cl)=OCCOc(cccc1)c1C(Nc(cc1)cc(C(F)(F)F)c1Cl)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Schotte A, et al. In vitro receptor binding and in vivo receptor occupancy in rat and guinea pig brain: risperidone compared with antipsychotics hitherto used. Jpn J Pharmacol. 1995 Dec;69(4):399-412.
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