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CG347B
CAS No. 1598426-03-9
CG347B( —— )
Catalog No. M23696 CAS No. 1598426-03-9
CG347B is a selective inhibitor of HDAC6.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 67 | In Stock |
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| 5MG | 110 | In Stock |
|
| 10MG | 177 | In Stock |
|
| 25MG | 318 | In Stock |
|
| 50MG | 484 | In Stock |
|
| 100MG | 672 | In Stock |
|
| 500MG | 1404 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCG347B
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NoteResearch use only, not for human use.
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Brief DescriptionCG347B is a selective inhibitor of HDAC6.
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DescriptionCG347B is a selective inhibitor of HDAC6.
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In VitroHtrA1 is identified as a Cisplatin (HY-17394, CDDP) resistance-related gene in NSCLC cells, while CG347B shows no effect on normalized mRNA expression or protein level of HtrA1 in NCI-H460 (CDDP-resistant) cells.CG347B (200 nM; 48 h) slightly rescues the Foxp3 expression inhibition induced by IL-4 (15 ng/mL), indicating a potential inhibition happens on histone deacetylation in naive CD4+ T cells from WT B6 mice cultured under Treg-polarizing conditions (for 1-3 d).
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetHDAC
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RecptorHDAC6
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Research Area——
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Indication——
Chemical Information
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CAS Number1598426-03-9
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Formula Weight283.33
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Molecular FormulaC16H17N3O2
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Purity>98% (HPLC)
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SolubilityDMSO:249 mg/mL?(878.83 mM;?Need ultrasonic)
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SMILESCCOC(c1cnc(NC2(CC2)c2ccccc2)nc1)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Christopher M. YATES. Metalloenzyme inhibitor compounds. WO2018165520A1.
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