CCMI( AVL-3288 )

Catalog No. M20774 CAS No. 917837-54-8

CCMI is a potent and selective modulator of α7 nAChR-positive allosteric.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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10MG	88	In Stock
25MG	178	In Stock
50MG	268	In Stock
100MG	411	In Stock
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Biological Information

Product Name

CCMI
Note

Research use only, not for human use.
Brief Description

CCMI is a potent and selective modulator of α7 nAChR-positive allosteric.
Description

CCMI is a potent and selective modulator of α7 nAChR-positive allosteric.
In Vitro

CCMI (Compound 6) is a potent and selective α7 nAChR-positive allosteric modulator, does not bind to or activate α7 nAChRs via the orthosteric site, and causes significant positive modulation of agonist-induced currents at α7 nAChRs.
In Vivo

——
Synonyms

AVL-3288
Pathway

Endocrinology/Hormones
Target

AChR
Recptor

nAChR
Research Area

——
Indication

——

Chemical Information

CAS Number

917837-54-8
Formula Weight

388.25
Molecular Formula

C19H15Cl2N3O2
Purity

>98% (HPLC)
Solubility

DMSO:100 mg/mL (257.57 mM)
SMILES

Cc1cc(/C(=C/Nc2ccc(Cl)cc2)C(=O)Nc2ccc(Cl)cc2)on1
Chemical Name

(Z)-3-(4-Chloroanilino)-N-(4-chlorophenyl)-2-(3-methylisoxazol-5-yl)prop-2-enamide

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Ng H J Whittemore E R Tran M B et al. Nootropic ?7 nicotinic receptor allosteric modulator derived from GABAA receptor modulators[J]. Proceedings of the National Academy of Sciences 2007 104(19):8059-8064.

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