BuChE-IN-TM-10( —— )

Catalog No. M32819 CAS No. 2313524-95-5

BuChE-IN-TM-10 (TM-10) is a potent inhibitor of butyrylcholinesterase (BuChE) with an IC50 of 8.9 nM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

BuChE-IN-TM-10
Note

Research use only, not for human use.
Brief Description

BuChE-IN-TM-10 (TM-10) is a potent inhibitor of butyrylcholinesterase (BuChE) with an IC50 of 8.9 nM.
Description

BuChE-IN-TM-10 (TM-10) is a potent butyrylcholinesterase (BuChE) inhibitor, with an IC50 of 8.9 nM. BuChE inhibitor 1 inhibits and disaggregates self-induced Aβ aggregation, exhibiting potent antioxidant activity and good blood-brain barrier (BBB) penetration. Has potential to treat Alzheimer’s disease.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Cell Cycle/DNA Damage
Target

AChR
Recptor

AChR
Research Area

——
Indication

——

Chemical Information

CAS Number

2313524-95-5
Formula Weight

498.66
Molecular Formula

C32H38N2O3
Purity

>98% (HPLC)
Solubility

——
SMILES

C(/C=C/C1=CC(OC)=C(OCCCCN(CC2=CC=CC=C2)CC)C=C1)(=O)N3CC=4C(CC3)=CC=CC4
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Sang Z, et al. Design, Synthesis, and Evaluation of Novel Ferulic Acid Derivatives as Multi-Target-Directed Ligands for the Treatment of Alzheimer's Disease. ACS Chem Neurosci. 2019 Feb 20;10(2):1008-1024.?

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