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BW-A78U

CAS No. 101155-02-6

BW-A78U( —— )

Catalog No. M19920 CAS No. 101155-02-6

BW-A 78U is a PDE4 inhibitor (IC50: 3 μM). It is not inhibition on the lipopolysaccharide (LPS)-induced TNF-α release.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    BW-A78U
  • Note
    Research use only, not for human use.
  • Brief Description
    BW-A 78U is a PDE4 inhibitor (IC50: 3 μM). It is not inhibition on the lipopolysaccharide (LPS)-induced TNF-α release.
  • Description
    BW-A 78U is a PDE4 inhibitor (IC50: 3 μM). It is not inhibition on the lipopolysaccharide (LPS)-induced TNF-α release.
  • In Vitro
    BW-A 78U is a PDE4 inhibitor with an IC50 of 3 μM. BW-A 78U fails to significantly inhibit arachidonate release.BW-A 78U is ineffective to inhibit the lipopolysaccharide (LPS)-induced TNF-α release.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    PDE
  • Recptor
    PDE4
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    101155-02-6
  • Formula Weight
    257.27
  • Molecular Formula
    C13H12FN5
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 100 mg/mL
  • SMILES
    CNc1ncnc2n(Cc3ccccc3F)cnc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Boichot E et al. Anti-inflammatory activities of a new series of selective phosphodiesterase 4 inhibitors derivedfrom 9-benzyladenine. J Pharmacol Exp Ther. 2000 Feb;292(2):647-53.
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