Antiviral agent 34( —— )

Catalog No. M37003 CAS No. 945152-88-5

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

Antiviral agent 34
Note

Research use only, not for human use.
Brief Description

Antiviral agent 34 is an orally available, potent antiviral compound that inhibits influenza A and B viruses.
Description

Antiviral agent 34 is a potent and orally active antiviral agent against influenza A and B subtypes with an EC50 value of 0.8 nM for H1N1 proliferation. Antiviral agent 34 derivatives inhibited influenza virus proliferation by targeting influenza virus RNA-dependent RNA polymerase. Antiviral agent 34 can be used for influenza virus research.
In Vitro

Cell Viability Assay Cell Line:MDCK cellsConcentration:0-470 nMIncubation Time:24 h Result:Exhibited low toxicity to MDCK cells.Western Blot Analysis Cell Line:MDCK cells Concentration:2-125 nM Incubation Time:24 h Result:Reduced the protein level of H1N1 nucleocapsid protein (NP) with low nanomolar values.Real Time qPCR Cell Line:MDCK cells Concentration:2-31.3 nM Incubation Time:24 h Result:Reduced the mRNA level of H1N1 nucleocapsid protein (NP) with low nanomolar values.
In Vivo

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Synonyms

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Pathway

Immunology/Inflammation
Target

Antiviral
Recptor

Antiviral | DNA/RNA Synthesis
Research Area

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Indication

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CAS Number

945152-88-5
Formula Weight

487.66
Molecular Formula

C29H33N3O2S
Purity

>98% (HPLC)
Solubility

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SMILES

O=C(NC1=CC=C(C=C1)NC(=S)NC(=O)C2=CC=C(C=C2)C(C)(C)C)C3=CC=C(C=C3)C(C)(C)C
Chemical Name

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