Aminopeptidase-IN-1( —— )

Catalog No. M35538 CAS No. 374102-08-6

Aminopeptidase-IN-1 is a potent inhibitor of insulin-regulated aminopeptidase (IRAP) (Ki: 7.7 μM).Aminopeptidase-IN-1 can be used in studies of cognitive and memory disorders.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Aminopeptidase-IN-1
Note

Research use only, not for human use.
Brief Description

Aminopeptidase-IN-1 is a potent inhibitor of insulin-regulated aminopeptidase (IRAP) (Ki: 7.7 μM).Aminopeptidase-IN-1 can be used in studies of cognitive and memory disorders.
Description

Aminopeptidase-IN-1 (compound 16o) is a potent insulin-regulated aminopeptidase (IRAP) inhibitor with an Ki value of 7.7 μM. Aminopeptidase-IN-1 can be used tor research cognitive and memory impairments.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Metabolic Enzyme/Protease
Target

Aminopeptidase
Recptor

Aminopeptidase
Research Area

——
Indication

——

Chemical Information

CAS Number

374102-08-6
Formula Weight

356.33
Molecular Formula

C18H16N2O6
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (280.64 mM; Ultrasonic )
SMILES

CCOC(=O)C1=C(N)Oc2cc(O)ccc2C1c1ccc(cc1)[N+]([O-])=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Mountford SJ, et al. Synthesis, structure-activity relationships and brain uptake of a novel series of benzopyran inhibitors of insulin-regulated aminopeptidase. J Med Chem. 2014 Feb 27;57(4):1368-77.?

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