Aminopeptidase-IN-1

CAS No. 374102-08-6

Aminopeptidase-IN-1( —— )

Catalog No. M35538 CAS No. 374102-08-6

Aminopeptidase-IN-1 is a potent inhibitor of insulin-regulated aminopeptidase (IRAP) (Ki: 7.7 μM).Aminopeptidase-IN-1 can be used in studies of cognitive and memory disorders.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 37 Get Quote
10MG 52 Get Quote
25MG 97 Get Quote
50MG 150 Get Quote
100MG 219 Get Quote
500MG 529 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Aminopeptidase-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    Aminopeptidase-IN-1 is a potent inhibitor of insulin-regulated aminopeptidase (IRAP) (Ki: 7.7 μM).Aminopeptidase-IN-1 can be used in studies of cognitive and memory disorders.
  • Description
    Aminopeptidase-IN-1 (compound 16o) is a potent insulin-regulated aminopeptidase (IRAP) inhibitor with an Ki value of 7.7 μM. Aminopeptidase-IN-1 can be used tor research cognitive and memory impairments.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Aminopeptidase
  • Recptor
    Aminopeptidase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    374102-08-6
  • Formula Weight
    356.33
  • Molecular Formula
    C18H16N2O6
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (280.64 mM; Ultrasonic )
  • SMILES
    CCOC(=O)C1=C(N)Oc2cc(O)ccc2C1c1ccc(cc1)[N+]([O-])=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Mountford SJ, et al. Synthesis, structure-activity relationships and brain uptake of a novel series of benzopyran inhibitors of insulin-regulated aminopeptidase. J Med Chem. 2014 Feb 27;57(4):1368-77.?
molnova catalog
related products
  • JNJ-4929821

    JNJ-4929821 is a potent, reversible methionine aminopeptidase-2 (MetAP-2) inhibitor with IC50 of 8 nM.

  • A-357300

    A-357300 is a potent, selective, reversible MetAP2 inhibitor with IC50 of 0.12 uM.

  • SC-22716

    SC-22716 is an orally active leukotriene A4 (LTA4) hydrolase inhibitor.SC-22716 has potential anti-inflammatory activity and may be used in the study of inflammatory bowel disease and psoriasis.