AS-136A( —— )

Catalog No. M35620 CAS No. 949898-66-2

AS-136A is an orally active measles virus RNA-dependent RNA polymerase (RdRp) inhibitor with antiviral activity that inhibits measles virus and blocks viral RNA synthesis.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
2MG	445	Get Quote
5MG	686	Get Quote
10MG	938	Get Quote
25MG	1398	Get Quote
50MG	1822	Get Quote
500MG	Get Quote	Get Quote
1G	Get Quote	Get Quote

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Biological Information

Product Name

AS-136A
Note

Research use only, not for human use.
Brief Description

AS-136A is an orally active measles virus RNA-dependent RNA polymerase (RdRp) inhibitor with antiviral activity that inhibits measles virus and blocks viral RNA synthesis.
Description

AS-136A is an orally active non-nucleoside inhibitor of the measles virus RNA-dependent RNA polymerase (RdRp) with an IC50 of 2 μM for measles virus.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Cell Cycle/DNA Damage
Target

DNA/RNA Synthesis
Recptor

DNA/RNA Synthesis
Research Area

——
Indication

——

Chemical Information

CAS Number

949898-66-2
Formula Weight

416.42
Molecular Formula

C17H19F3N4O3S
Purity

>98% (HPLC)
Solubility

——
SMILES

O=C(NC1=CC=C(C=C1)S(=O)(=O)N2CCCCC2)C3=CC(=NN3C)C(F)(F)F
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Ndungu JM, et al. Non-nucleoside inhibitors of the measles virus RNA-dependent RNA polymerase: synthesis, structure-activity relationships, and pharmacokinetics. J Med Chem. 2012;55(9):4220-4230.?

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