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AGPS-IN-2i
CAS No. 2316782-88-2
AGPS-IN-2i( —— )
Catalog No. M36301 CAS No. 2316782-88-2
AGPS-IN-2i is a potent and high-affinity inhibitor of alkylglycerol phosphate synthase that controls ether lipid utilization and metabolism in cells, reduces ether lipid levels and cell migration, and promotes proliferation and motility of cancer cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | 600 | Get Quote |
|
| 50MG | 779 | Get Quote |
|
| 100MG | 1152 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameAGPS-IN-2i
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NoteResearch use only, not for human use.
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Brief DescriptionAGPS-IN-2i is a potent and high-affinity inhibitor of alkylglycerol phosphate synthase that controls ether lipid utilization and metabolism in cells, reduces ether lipid levels and cell migration, and promotes proliferation and motility of cancer cells.
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DescriptionAGPS-IN-1 (Compound 2i) is an effective AGPS binder. AGPS-IN-1 reduces ether lipids levels and cell migration rate. AGPS-IN-1 inhibits epithelial-mesenchymal transition (EMT) in prostate PC-3 and breast MDA-MB-231 cancer cells.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetMMP
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RecptorMMP
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Research Area——
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Indication——
Chemical Information
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CAS Number2316782-88-2
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Formula Weight345.34
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Molecular FormulaC18H17F2N3O2
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Purity>98% (HPLC)
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Solubility——
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SMILESC(NC(CC(C)C1=C(F)C=CC=C1F)=O)C=2C=C3C(=CC2)NC(=O)N3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Histatin 5 TFA inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μM, respectively.Histatin 5 is a member of a family of low-molecular-weight salivary proteins secreted by parotid, submandibular, and sublingual glands. Using biotinylated gelatin as a substrate, Histatin 5 is found to inhibit the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μM, respectively.
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ND-322 HCl
ND-322 HCl (ND 322 Hydrochloride) is a selective inhibitor of MT1-MMP and MMP2 and reduces in vitro melanoma cell growth, migration and invasion.
