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Home - Products - Immunology/Inflammation - Lipoxygenase - 5-LOX-IN-1

5-LOX-IN-1

CAS No. 55040-82-9

5-LOX-IN-1( —— )

Catalog No. M35529 CAS No. 55040-82-9

5-LOX-IN-1 is a 5-Lipoxygenase (5-LOX) inhibitor (IC50: 2.3 μM).5-LOX-IN-1 can be used for cancer research.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    5-LOX-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    5-LOX-IN-1 is a 5-Lipoxygenase (5-LOX) inhibitor (IC50: 2.3 μM).5-LOX-IN-1 can be used for cancer research.
  • Description
    5-LOX-IN-1 (compound 2b) is an inhibitor of human 5-Lipoxygenase (5-LOX) with an IC50 value of 2.3 μM. 5-LOX-IN-1 can be used for the research of inflammation.
  • In Vitro
    5-LOX-IN-1 (0-10 μM) inhibits 5-LOX with an IC50 value of 2.3 μM.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Immunology/Inflammation
  • Target
    Lipoxygenase
  • Recptor
    Lipoxygenase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    55040-82-9
  • Formula Weight
    350.43
  • Molecular Formula
    C20H18N2O2S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (285.36 mM; Ultrasonic (<60°C)
  • SMILES
    O=C(c1sc(nc1-c1ccccc1)N1CCOCC1)c1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Sinha S, et al. Design, synthesis and identification of novel substituted 2-amino thiazole analogues as potential anti-inflammatory agents targeting 5-lipoxygenase. Eur J Med Chem. 2018 Oct 5;158:34-50.?
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