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2-TEDC

CAS No. 132465-10-2

2-TEDC( —— )

Catalog No. M33822 CAS No. 132465-10-2

2-TEDC is a potent lipoxygenase (LOX) inhibitor with inhibitory effects on 5-LOX, 12-LOX, and 15-LOX with IC50 values of 0.09 μM, 0.013 μM, and 0.5 μM, respectively.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

2-TEDC
Note

Research use only, not for human use.
Brief Description

2-TEDC is a potent lipoxygenase (LOX) inhibitor with inhibitory effects on 5-LOX, 12-LOX, and 15-LOX with IC50 values of 0.09 μM, 0.013 μM, and 0.5 μM, respectively.
Description

2-TEDC is a potent inhibitor of 5-, 12-, and 15-lipoxygenase with IC50 values of 0.09 μM, 0.013 μM and 0.5 μM, respectively. 2-TEDC can be used for the research of atheroscrelosi.
In Vitro

2-TEDC can potent inhibit 5-, 12-, and 15-lipoxygenase with IC50 values of 0.09 μM, 0.013 μM and 0.5 μM, respectively.
In Vivo

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Synonyms

——
Pathway

Immunology/Inflammation
Target

Lipoxygenase
Recptor

Lipoxygenase
Research Area

——
Indication

——

Chemical Information

CAS Number

132465-10-2
Formula Weight

315.34
Molecular Formula

C16H13NO4S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (317.12 mM; Ultrasonic )
SMILES

Oc1ccc(\C=C(/C#N)C(=O)OCCc2cccs2)cc1O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. H Cho, et al. Novel caffeic acid derivatives: extremely potent inhibitors of 12-lipoxygenase. J Med Chem. 1991 Apr;34(4):1503-5. ?

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