2-D08

CAS No. 144707-18-6

2-D08( —— )

Catalog No. M20719 CAS No. 144707-18-6

2-D08 is a synthetic flavone that inhibits sumoylation also inhibits Axl with an IC50 of 0.49 nM.2-D08 showed anti-aggregatory and neuroprotective effect.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 47 In Stock
10MG 80 In Stock
25MG 170 In Stock
50MG 267 In Stock
100MG 484 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    2-D08
  • Note
    Research use only, not for human use.
  • Brief Description
    2-D08 is a synthetic flavone that inhibits sumoylation also inhibits Axl with an IC50 of 0.49 nM.2-D08 showed anti-aggregatory and neuroprotective effect.
  • Description
    2-D08 is a synthetic flavone that inhibits sumoylation also inhibits Axl with an IC50 of 0.49 nM.2-D08 showed anti-aggregatory and neuroprotective effect.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Proteasome/Ubiquitin
  • Target
    E1
  • Recptor
    sumoylation|AXL
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    144707-18-6
  • Formula Weight
    270.24
  • Molecular Formula
    C15H10O5
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:150 mg/mL (555.06 mM)
  • SMILES
    Oc1ccc(-c2cc(=O)c3ccccc3o2)c(O)c1O
  • Chemical Name
    2-(234-trihydroxyphenyl)-4H-1-benzopyran-4-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kim Y Nagy K Keyser S et al. An Electrophoretic Mobility Shift Assay Identifies a Mechanistically Unique Inhibitor of Protein Sumoylation[J]. Chemistry & Biology 2013 20(4):604-613.
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