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17β-HSD10-IN-1
CAS No. 2316765-78-1
17β-HSD10-IN-1( —— )
Catalog No. M36963 CAS No. 2316765-78-1
17β-HSD10-IN-1 is an orally available 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10) inhibitor with blood-brain permeability and potency for the study of Alzheimer's disease.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 57 | Get Quote |
|
| 10MG | 93 | Get Quote |
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| 25MG | 181 | Get Quote |
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| 50MG | 293 | Get Quote |
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| 100MG | 447 | Get Quote |
|
| 500MG | 981 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product Name17β-HSD10-IN-1
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NoteResearch use only, not for human use.
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Brief Description17β-HSD10-IN-1 is an orally available 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10) inhibitor with blood-brain permeability and potency for the study of Alzheimer's disease.
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Description17β-HSD10-IN-1 (compound 9) is an orally active inhibitor of 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10) with blood-brain permeability. 17β-HSD10-IN-1 doesn't result additional effects for mitochondrial off-targets and cytotoxic or neurotoxic effects.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetDehydrogenase
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RecptorDehydrogenase | Endogenous Metabolite
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Research Area——
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Indication——
Chemical Information
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CAS Number2316765-78-1
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Formula Weight376.82
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Molecular FormulaC16H13ClN4O3S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 25 mg/mL (66.34 mM; Ultrasonic )
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SMILESO=C(NC1=NC=2C=CC(=CC2S1)NC(=O)C)NC3=CC=C(O)C(Cl)=C3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Benek O, et al. Development of submicromolar 17尾-HSD10 inhibitors and their in vitro and in vivo evaluation. Eur J Med Chem. 2023 Oct 5;258:115593.聽?
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