JB002

JB002

Catalog No. M36394

JB002, a myosin II inhibitor, exhibits potent activity with an IC50 of ≤10 μM. It holds potential for research applications in muscle spasticity, chronic musculoskeletal pain, and hypertrophic cardiomyopathy.

Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 180 In Stock
5MG 163 In Stock
10MG 264 In Stock
25MG 535 In Stock
50MG 731 In Stock
100MG 1014 In Stock
200MG Get Quote In Stock
500MG 2027 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    JB002
  • Brief Description
  • Description
  • Storage
  • Note
    Research use only, not for human use.
  • Reference
    1. Smith JD, et, al. Isoform selectivities of novel 4-hydroxycoumarin imines as inhibitors of myosin II. Eur J Med Chem. 2022 Dec 12;247:115008. ?
molnova catalog
related products
  • Mavacamten

    Mavacamten (SAR-439152, MYK-461) is a small molecule that reduces contractility by decreasing the ATPase activity of the cardiac myosin heavy chain.

  • MS-444

    MS-444 (BE-34776) is a smooth muscle myosin light chain kinase (MLCK) and HuR inhibitor with antitumor activity for triple-negative breast and colorectal cancer.

  • JB062

    JB062 is a chemical compound acting as a nonmuscle myosin inhibitor, exhibiting IC50 values of 1.6, 5.4, and >100 μM against skeletal muscle myosin, cardiac muscle myosin, and smooth muscle myosin II, respectively.