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α-Glucosidase-IN-23

CAS No. 161187-57-1

α-Glucosidase-IN-23( —— )

Catalog No. M35940 CAS No. 161187-57-1

α-Glucosidase-IN-23 is an orally active inhibitor of α-glucosidase that can decrease blood glucose levels by inhibiting α-glucosidase (IC50 = 4.48 μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    α-Glucosidase-IN-23
  • Note
    Research use only, not for human use.
  • Brief Description
    α-Glucosidase-IN-23 is an orally active inhibitor of α-glucosidase that can decrease blood glucose levels by inhibiting α-glucosidase (IC50 = 4.48 μM).
  • Description
    α-Glucosidase-IN-23 is an orally active α-Glucosidase inhibitor. α-Glucosidase-IN-23 decreases blood glucose by a-glucosidase inhibition with an IC50 value of 4.48 μM. α-Glucosidase-IN-23 can be used for the research of diabetes.
  • In Vitro
    Cell Proliferation AssayCell Line:INS-1 Cells Concentration:1 μM Incubation Time:Result:Stimulated the growth of INS-1 cells in a dose-codependent approach.Apoptosis AnalysisCell Line:INS-1 Cells Concentration:1 μM Incubation Time:Result:Restored the viability of INS-1 cells by about five times from apoptosis and eight times from necrosis.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Glucosidase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    161187-57-1
  • Formula Weight
    373.4
  • Molecular Formula
    C20H23NO6
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(OCC)(=O)C=1C(C(C(OCC)=O)=C(C)NC1C)C2=C3C(=CC=C2)OCO3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Peter A Sidhom, et al. Mechanistic Insight of Synthesized 1,4-Dihydropyridines as an Antidiabetic Sword against Reactive Oxygen Species. J Med Chem. 2023 Jan 12;66(1):991-1010. ?
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