α-Bungarotoxin

Research use only, not for human use.

Neurotoxin that blocks neuromuscular transmission via irreversible inhibition of nicotinic ACh receptors (nAChRs). Prevents opening of nicotinic receptor-associated ion channels and is selective for α7 receptors over α3β4 receptors (IC50 values are 1.6 nM and > 3 μM respectively).

Neurotoxin that blocks neuromuscular transmission via irreversible inhibition of nicotinic ACh receptors (nAChRs). Prevents opening of nicotinic receptor-associated ion channels and is selective for α7 receptors over α3β4 receptors (IC50 values are 1.6 nM and > 3 μM respectively).

α-Bungarotoxin binds specifically and with high affinity to the nicotinic acetylcholine receptor and competes with binding of the natural ligand. α-Bungarotoxin (α-BTX), is a potent competitive inhibitors of nicotinic acetylcholine receptor function and is highly toxic due to functional blockade of AcChoRs at the neuromuscular junction.

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Endocrinology/Hormones

AChR

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11032-79-4

7984.14

C338H529N97O105S11

>98% (HPLC)

water:Soluble

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(-20℃)

With Ice Pack

≥ 2 years