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m-PEG8-Ms
CAS No. 1059588-19-0
m-PEG8-Ms( —— )
Catalog No. M33420 CAS No. 1059588-19-0
m-PEG8-Ms is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product Namem-PEG8-Ms
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NoteResearch use only, not for human use.
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Brief Descriptionm-PEG8-Ms is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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Descriptionm-PEG8-Ms is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG8-Ms is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
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In Vivo——
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Synonyms——
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PathwayAntibody Drug Conjugates (ADC)
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TargetADCs Linker/Click Chemistry
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RecptorADC Linker
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Research Area——
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Indication——
Chemical Information
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CAS Number1059588-19-0
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Formula Weight462.55
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Molecular FormulaC18H38O11S
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Purity>98% (HPLC)
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Solubility——
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SMILESO=S(=O)(OCCOCCOCCOCCOCCOCCOCCOCCOC)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Sanxing Sun, et al. Triazolotriazine derivatives as a2a receptor antagonists. WO2020002969A1.
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