hSMG-1 inhibitor 11e
CAS No. 1402452-10-1
hSMG-1 inhibitor 11e( —— )
Catalog No. M28042 CAS No. 1402452-10-1
hSMG-1 inhibitor 11e is a potent and selective hSMG-1 kinase inhibitor with an IC50 of 900-fold selectivity over mTOR (IC50 of 45 nM), PI3Kα/γ (IC50s of 61 nM and 92 nM) and CDK1/CDK2 (IC50s of 32 μM and 7.1 μM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 429 | In Stock |
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| 5MG | 376 | In Stock |
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| 10MG | 464 | In Stock |
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| 25MG | 748 | In Stock |
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| 50MG | 986 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NamehSMG-1 inhibitor 11e
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NoteResearch use only, not for human use.
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Brief DescriptionhSMG-1 inhibitor 11e is a potent and selective hSMG-1 kinase inhibitor with an IC50 of 900-fold selectivity over mTOR (IC50 of 45 nM), PI3Kα/γ (IC50s of 61 nM and 92 nM) and CDK1/CDK2 (IC50s of 32 μM and 7.1 μM).
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DescriptionhSMG-1 inhibitor 11e is a potent and selective hSMG-1 kinase inhibitor with an IC50 of 900-fold selectivity over mTOR (IC50 of 45 nM), PI3Kα/γ (IC50s of 61 nM and 92 nM) and CDK1/CDK2 (IC50s of 32 μM and 7.1 μM).(In Vitro):hSMG-1 inhibitor 11e exhibits an IC50 of 900-fold selectivity over mTOR (IC50 = 45 nM), PI3Kα/γ (IC50 = 61 nM), PI3Kγ (IC50 = 92 nM), CDK1(IC50 = 32 μM) and CDK2 (IC50 = 7.1 μM).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorCOX-1|COX-2|Xanthine Oxidase
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Research Area——
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Indication——
Chemical Information
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CAS Number1402452-10-1
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Formula Weight517.6
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Molecular FormulaC26H27N7O3S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (96.60 mM)
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SMILESN/A
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Acacetin 7-O-(6-O-malonylglucoside) is a monoamine oxidase inhibitor with strong inhibitory effects on monoamine oxidase A (MAO-A) and monoamine oxidase B (MAO-B) with IC50 values ??of 2.34and 1.87 μM, respectively. Acacetin 7-O-(6-O-malonylglucoside) is a reversible MAO inhibitor that can be used in the research of neurodegenerative diseases and affective disorders.
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