eCF506

Research use only, not for human use.

eCF506 is a potent and selective inhibitor of SRC (IC50 < 0.5 nM)eCF506, the first small molecule with subnanomolar IC50 for SRC that requires 3 orders of magnitude greater concentration to inhibit ABL.?

eCF506 is a potent and selective inhibitor of SRC (IC50 < 0.5 nM)eCF506, the first small molecule with subnanomolar IC50 for SRC that requires 3 orders of magnitude greater concentration to inhibit ABL.?eCF506 exhibits excellent water solubility, an optimal DMPK profile and oral bioavailability, halts SRC-associated neuromast migration in zebrafish embryos without inducing life-threatening heart defects, and inhibits SRC phosphorylation in tumor xenografts in mice.

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Tyrosine Kinase

Src

Src

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1914078-41-3

510.63

C26H38N8O3

>98% (HPLC)

DMSO:62.5 mg/mL (122.40 mM; Need ultrasonic)

COc1cc(ccc1NC(=O)OC(C)(C)C)-c1nn(CCN2CCC(CC2)N(C)C)c2ncnc(N)c12

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(-20℃)

With Ice Pack

≥ 2 years