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Zucapsaicin

CAS No. 25775-90-0

Zucapsaicin( BRN 4261852 | cis-Capsaicin | Civamide | Zucapsaicin )

Catalog No. M13778 CAS No. 25775-90-0

Zucapsaicin (Civanex) is a medication used to treat osteoarthritis of the knee and Others neuropathic pain.Zucapsaicin is a synthetic cis isomer of natural capsaicin that has shown therapeutic efficacy in pain accompanying osteoarthritis of the knee.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Zucapsaicin
  • Note
    Research use only, not for human use.
  • Brief Description
    Zucapsaicin (Civanex) is a medication used to treat osteoarthritis of the knee and Others neuropathic pain.Zucapsaicin is a synthetic cis isomer of natural capsaicin that has shown therapeutic efficacy in pain accompanying osteoarthritis of the knee.
  • Description
    Zucapsaicin (Civanex) is a medication used to treat osteoarthritis of the knee and Others neuropathic pain.Zucapsaicin is a synthetic cis isomer of natural capsaicin that has shown therapeutic efficacy in pain accompanying osteoarthritis of the knee. (In Vitro):(Z)-Capsaicin is the cis isomer of capsaicin, acting as a TRPV1 agonist. (Z)-Capsaicin may also blocks the neruonal calcium channel.(In Vivo):(Z)-Capsaicin (Zucapsaicin) significantly attenuates nociceptive behavior after oral administration in rats. (Z)-Capsaicin is also tolerated in the primary or recurrent experimental genital herpes simplex virus infection in guinea pigs.
  • In Vitro
    (Z)-Capsaicin is the cis isomer of capsaicin, acting as a TRPV1 agonist. (Z)-Capsaicin may also blocks the neruonal calcium channel.
  • In Vivo
    (Z)-Capsaicin (Zucapsaicin) significantly attenuates nociceptive behavior after oral administration in rats. (Z)-Capsaicin is also tolerated in the primary or recurrent experimental genital herpes simplex virus infection in guinea pigs.
  • Synonyms
    BRN 4261852 | cis-Capsaicin | Civamide | Zucapsaicin
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    25775-90-0
  • Formula Weight
    305.41
  • Molecular Formula
    C18H27NO3
  • Purity
    >98% (HPLC)
  • Solubility
    Soluble in DMSO
  • SMILES
    CC(C)/C=C\CCCCC(NCC1=CC=C(O)C(OC)=C1)=O
  • Chemical Name
    (Z)-N-(4-hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Sa?at K, et al. Expert Opin Investig Drugs. 2014 Oct;23(10):1433-40.
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