ZY-19489( —— )

Catalog No. M35924 CAS No. 1821293-40-6

ZY-19489 is an antimalarial compound that is a potential single-dose cure for Plasmodium falciparum and Plasmodium vivax malaria. It has received orphan drug designation from the FDA.

Purity : >98% (HPLC)

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10MG	1121	Get Quote
25MG	1647	Get Quote
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Biological Information

Product Name

ZY-19489
Note

Research use only, not for human use.
Brief Description

ZY-19489 is an antimalarial compound that is a potential single-dose cure for Plasmodium falciparum and Plasmodium vivax malaria. It has received orphan drug designation from the FDA.
Description

Sutidiazine (ZY-19489) is an orally active and antimalarial agent. Sutidiazine inhibits parasitemia-induced infection. Sutidiazine shows short half-lives (approximately 7 h) and an exposure effect.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Microbiology/Virology
Target

Parasite
Recptor

Parasite
Research Area

——
Indication

——

Chemical Information

CAS Number

1821293-40-6
Formula Weight

465.57
Molecular Formula

C24H32FN9
Purity

>98% (HPLC)
Solubility

——
SMILES

N(C=1C(=CN=C(NC2=CC(=C(F)C(C)=N2)C3CC3)N1)N4C[C@@H](C)N(C)CC4)C=5C=C(C)N(C)N5
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Ghoghari AM, et al. Simultaneous estimation of ZY-19489 and its active metabolite?ZY-20486 in human plasma using LC-MS/MS, a novel antimalarial compound. Bioanalysis. 2021 Dec;13(23):1761-1777.?

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