ZIM( —— )

Catalog No. M36395 CAS No. 301298-87-3

ZIM, a norbornene derivative of 4-Aminoantipyrine, effectively induces DNA damage, leading to genomic and chromosomal alterations, cell death, and phagocytosis activation.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

ZIM
Note

Research use only, not for human use.
Brief Description

ZIM, a norbornene derivative of 4-Aminoantipyrine, effectively induces DNA damage, leading to genomic and chromosomal alterations, cell death, and phagocytosis activation.
Description

ZIM, a norbornene derived from 4-Aminoantipyrine, is a potent inducer of DNA damage, causing genomic and chromosomal damage as well as inducing cell death and activating phagocytosis. ZIM has chemotherapeutic potential for use in cancer research.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Cell Cycle/DNA Damage
Target

DNA/RNA Synthesis
Recptor

DNA/RNA Synthesis
Research Area

——
Indication

——

Chemical Information

CAS Number

301298-87-3
Formula Weight

349.38
Molecular Formula

C20H19N3O3
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 50 mg/mL (143.11 mM; Ultrasonic (<60°C)
SMILES

CN1N(C(=O)C(N2C(=O)C3C4CC(C=C4)C3C2=O)=C1C)C1=CC=CC=C1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Rodrigo Juliano Oliveira, et al. ZIM, a Norbornene Derived from 4-Aminoantipyrine, Induces DNA Damage and Cell Death but in Association Reduces the Effect of Commercial Chemotherapeutics. Chem Res Toxicol. 2022 Dec 22.??

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