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Home - Products - Chromatin/Epigenetic - Histone Demethylase - YF-2

YF-2

CAS No. 1311423-89-8

YF-2( YF 2 )

Catalog No. M20208 CAS No. 1311423-89-8

YF-2 is blood-brain-barrier permeable histone acetyltransferase activator acetylates H3 in the hippocampus ?CBP PCAF and GCN5 with EC50s of 2.75 μM 29.04 μM and 49.31 μM respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    YF-2
  • Note
    Research use only, not for human use.
  • Brief Description
    YF-2 is blood-brain-barrier permeable histone acetyltransferase activator acetylates H3 in the hippocampus ?CBP PCAF and GCN5 with EC50s of 2.75 μM 29.04 μM and 49.31 μM respectively.
  • Description
    YF-2 is blood-brain-barrier permeable histone acetyltransferase activator acetylates H3 in the hippocampus ?CBP PCAF and GCN5 with EC50s of 2.75 μM 29.04 μM and 49.31 μM respectively.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    YF 2
  • Pathway
    Chromatin/Epigenetic
  • Target
    Histone Demethylase
  • Recptor
    CBP|PCAF|GCN5
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1311423-89-8
  • Formula Weight
    430.85
  • Molecular Formula
    C20H22ClF3N2O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:125 mg/mL (290.12 mM);Water:Insoluble
  • SMILES
    CCOc1cccc(OCCN(C)C)c1C(=O)Nc1ccc(Cl)c(c1)C(F)(F)F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.FENG Yen et al. HISTONE ACETYLTRANSFERASE ACTIVATORS AND USES THEREOF. WO 2011072243A1.
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