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Xenalipin

CAS No. 84392-17-6

Xenalipin( BW 207U )

Catalog No. M27180 CAS No. 84392-17-6

Xenalipin has hypolipidemic. It reduces blood cholesterol and triglycerides in rats.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Xenalipin
  • Note
    Research use only, not for human use.
  • Brief Description
    Xenalipin has hypolipidemic. It reduces blood cholesterol and triglycerides in rats.
  • Description
    Xenalipin has hypolipidemic. It reduces blood cholesterol and triglycerides in rats.
  • In Vitro
    ——
  • In Vivo
    4'-Trifluoromethyl-2-biphenyl carboxylic acid (15-60 mg/kg, p.o., twice a day) shows hypolipidemic activity in diet-induced hypercholesterolemic African green monkeys. Animal Model:Diet-induced hypercholesterolemic African green monkeys Dosage:15-60 mg/kg Administration:Oral administration (p.o.)Result:Reduced serum LDL-cholesterol concentrations.
  • Synonyms
    BW 207U
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    SIRT1| SIRT2| SIRT3
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    84392-17-6
  • Formula Weight
    266.219
  • Molecular Formula
    C14H9F3O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : ≥ 250 mg/mL (939.07 mM)
  • SMILES
    OC(=O)c1ccccc1-c1ccc(cc1)C(F)(F)F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Disch JS, et al. Discovery of thieno[3,2-d]pyrimidine-6-carboxamides as potent inhibitors of SIRT1, SIRT2, and SIRT3. J Med Chem. 2013 May 9;56(9):3666-79.
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