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XY028-133
CAS No. 2229974-73-4
XY028-133( —— )
Catalog No. M33174 CAS No. 2229974-73-4
XY028-133 is a PROTAC-based CDK4/6 degrader for the study of tumors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 181 | Get Quote |
|
| 5MG | 282 | Get Quote |
|
| 10MG | 496 | Get Quote |
|
| 25MG | 814 | Get Quote |
|
| 50MG | 1454 | Get Quote |
|
| 100MG | 2376 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameXY028-133
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NoteResearch use only, not for human use.
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Brief DescriptionXY028-133 is a PROTAC-based CDK4/6 degrader for the study of tumors.
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DescriptionXY028-133 (example 14) is a PROTAC-based CDK4/6 degrader with anti-tumor activity, which consists of ligands for von Hippel-Lindau and CDK.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorPROTACs | CDK
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Research Area——
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Indication——
Chemical Information
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CAS Number2229974-73-4
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Formula Weight1002.23
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Molecular FormulaC53H67N11O7S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (49.89 mM; Ultrasonic )
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SMILESCC(=O)c1c(C)c2cnc(Nc3ccc(cn3)N3CCN(CC3)C(=O)CCCCCC(=O)N[C@H](C(=O)N3C[C@H](O)C[C@H]3C(=O)NCc3ccc(cc3)-c3scnc3C)C(C)(C)C)nc2n(C2CCCC2)c1=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. JIN, Jian， et al. COMPOSITIONS AND METHODS FOR TREATING CDK4/6-MEDIATED CANCER. Patent. US2017/065027.
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